Hematopoietic stem cell biology and leukemogenesis

Alessandra Giorgetti

POSTDOCTORAL RESEARCHERS
  • Damià Romero Moya
PREDOCTORAL RESEARCHERS
  • Raimon Bundo Ruiz
  • Maria Magallon Mosella
  • Joan Pera Garcia
  • Zhichao Qiu
SCIENTIFIC SUPPORT
  • Eric Torralba Sales
Regenerative Medicine
Regenerative Medicine

5

PAPERS

Average IF: 13,96

3

LED PAPERS

Average IF: 14,17

5 PUBLICATIONS IN FIRST DECILE

5 PUBLICATIONS IN FIRST QUARTILE

5 PUBLICATIONS IN OPEN ACCESS

Research highlights

PROJECTS

1 Granted competitive project
8 Ongoing competitive projects

NETWORKS

3D-GATA2
SEHOP
SEHH
EHA
GESMD
SGR GRE 2021

Selected projects

  • Romero Moya,D;Torralba Sales,E;Calvo,C;Marin Bejar,O;Magallon Mosella,M;Distefano,M;Pera,J et al, CRISPR-engineered human GATA2 deficiency model uncovers mitotic dysfunction and premature aging in HSPCs, impairing hematopoietic fitness, Leukemia, 2025;39(12):3015-3025, doi:10.1038/s41375-025-02771-8
  • Pera,J;Romero Moya,D;Torralba Sales,E;Andersson,R;Garcia Hernandez,V;Magallon Mosella,M;Distefano,M et al, Human iPSCs-based modeling unveils SETBP1 as a driver of chromatin rewiring in GATA2 deficiency, Nat. Commun. 2025;16(1):10035-10035, doi:10.1038/s41467-025-65806-9
  • Romero Moya,D;Pera,J;Marin Bejar,O;Torralba Sales,E;Murillo Sanjuán,L;Diaz Heredia,C;Montoro,J et al, Multiple phenotypes and epigenetic profiles in a three-generation family history with GATA2 deficiency., Leukemia, 2025;39(4):962-966, doi:10.1038/s41375-025-02519-4
  • Kotmayer,L;Kozyra,EJ;Kang,G;Strahm,B;Yoshimi,A;Sahoo,SS;Pastor,VB et al, Age-dependent phenotypic and molecular evolution of pediatric MDS arising from GATA2 deficiency, Blood Cancer J, 2025;15(1):121-121, doi:10.1038/s41408-025-01309-6
  • Martínez García de la Torre,RA;Vallverdú,J;Xu,Z;Ariño,S;Ferrer Lorente,R;Zanatto,L;Mercado Gómez,M et al, Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis., Nat. Commun., 2025;16(1):1489-1489, doi:10.1038/s41467-025-56024-4

Selected projects

  • PID2023-146290OB-I00. Estudio del Papel del Nicho de Médula Osea en la Deficiencia de GATA2. Ministerio de Ciencia e Innovación. Budget: 318.750€. 2024-2027. PI: ALESSANDRA GIORGETTI.
  • AC23_2/00040. 3D-GATA2: How GATA2 Deficiency affects development and disease. Instituto de Salud Carlos III (ISCIII). Budget: 180.000€. 2024-2026. PI: ALESSANDRA GIORGETTI.
  • FORT23/00032_6 – FORTALECE ISCIII . Smart Health Community (SHC), promoviendo la medicina basada en el valor. Instituto de Salud Carlos III (ISCIII). Budget: 408.000€. 2024-2027. PI: ALESSANDRA GIORGETTI.
  • 24334797. EHAKoG2024 – Romero, D. EUROPEAN HEMATOLOGY ASSOCIATION EHA. Budget: 50.000€. 2025-2026. PI: DAMIA ROMERO MOYA.
  • DJCLS 13R/2022. Die Untersuchung genetischer und mechanistischer Auswirkungen einer Monosomie 7 bei der GATA2 Defizienz (Investigating genetic and mechanistic contributions of monosomy 7 in GATA2 deficiency). DEUTSCHE JOSÉ CARRERAS LEUKÄMIE-STIFTUNG E.V. Budget: 130.100€. 2022-2025. PI: ALESSANDRA GIORGETTI.